tag:blogger.com,1999:blog-8992792203139033798.post6329766972026108650..comments2023-06-28T14:46:33.317+01:00Comments on Acid Rabbi: Griffin acts like an idiotAcid Rabbihttp://www.blogger.com/profile/06627567621791730292noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-8992792203139033798.post-58178419606972281042009-07-09T04:15:22.587+01:002009-07-09T04:15:22.587+01:00The problem is the African population is set to do...The problem is the African population is set to double to 1.5 billion by 2050. This will place a major strain on Europe.<br /><br />Recent evidence of adaptive changes which involve neurological function suggest that group differences are partly hereditary. This is a problem because as you can see in Malaysia, if you have groups getting consistently different outcomes it leads to resentment and tension.<br /><br />A June 2007 article from Plos Genetics, Localizing Recent Adaptive Evolution in the Human Genome, provides examples of localized evolution of cognitive function.<br /><br />Several genes with functional roles in the development and function of the nervous system show very strong evidence (CLR p < 10−5) for a recent selective sweep. For example, SV2B, a gene encoding a synaptic vesicle protein with highest expression during brain development [36], exhibits strong evidence for a selective sweep in the African-American sample. Likewise, the protein encoded by DAB1 plays a developmental role in the layering of neurons in the cerebral cortex and cerebellum [37], and exhibits strong evidence for a selective sweep in the Asian sample. Other nervous system genes with strong evidence for a selective sweep include two candidate genes for Alzheimer disease (APPBP2 and APBA2) that bind the amyloid-beta precursor protein, two genes (SKP1A and PCDH15) with a role in sensory development, and several others with various roles in nervous system development and function (PHACTR1, ALG10, PREP, GPM6A, and DGKI).<br /><br /><br />A March 2007 article from Plos Biology, A Map of Recent Positive Selection in the Human Genome, finds plenty of signs up local cognitive evolution.<br /><br />Recent articles have proposed that genes involved in brain development and function may have been important targets of selection in recent human evolution [8,9]. While we do not find evidence for selection in the two genes reported in those studies (MCPH1 and ASPM), we do find signals in two other microcephaly genes, namely, CDK5RAP2 in Yoruba, and CENPJ in Europeans and East Asians [46]. Though there is not an overall enrichment for neurological genes in our gene ontology analysis, several other important brain genes also have signals of selection, including the primary inhibitory neurotransmitter GABRA4, an Alzheimer's susceptibility gene PSEN1, and SYT1 in Yoruba; the serotonin transporter SLC6A4 in Europeans and East Asians; and the dystrophin binding gene SNTG1 in all populations.Anonymousnoreply@blogger.com